Atrial fibrillation (AF) is the most common cardiac rhythm disturbance and represents a substantial clinical and public health issue. AF, particularly if inappropriately treated, is associated with poor patient outcomes such as heart failure, stroke and even death. Efforts to address the complex causes of AF are required to attenuate future AF-related morbidity, mortality and economic costs. In addition to increasing age, increase left atrium size, overweight, low and intensive physical activity, diabetes and prevalent cardiac disease, AF is associated with hypertension. The association between blood pressure trends over time with multiple measurements and AF in various age- and sex subgroups in general populations has not been extensively examined. Our study aims to evaluate how baseline blood pressure and blood pressure trends over time impact the incidence of AF in both genders and different age groups.